![]() ![]() ![]() The NIH-AARP Diet and Health Study was registered at as NCT00340015.How Much Caffeine in Decaf Coffee? Is Decaf Coffee Bad for You? How caffeine is stripped from coffee and what that means for your health Additional investigations of coffee intake and its components in the prevention of colorectal cancer by subsites are warranted. In this large US cohort, coffee was inversely associated with colon cancer, particularly proximal tumors. Although individual HRs were not significant, there was a significant P-trend for both colon and rectal cancers for people who drank predominantly decaffeinated coffee. Results were similar to those overall for drinkers of predominantly caffeinated coffee. Multivariable HRs and 95% CIs were estimated by using Cox regression.Īpproximately 16% of participants drank ≥4 cups coffee/d. ![]() Over a median of 10.5 y of follow-up, we identified 2863 proximal colon, 1993 distal colon, and 1874 rectal cancers. The NIH-AARP Diet and Health Study included 489,706 men and women who completed a baseline (1995-1996) self-administered questionnaire of demographics, diet, and lifestyle. We evaluated coffee and tea intakes (caffeinated and decaffeinated) in relation to colon (proximal and distal) and rectal cancers. Despite differences in gut physiology, few studies have conducted investigations by anatomic subsites. Epidemiologic data for coffee and tea intakes in relation to colorectal cancer remain unclear. Coffee and tea are widely consumed globally and are rich sources of potential chemopreventive compounds. ![]()
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